Sikander Khan, D.O.’12, M.S.

Sikander Khan, D.O.’12, M.S., a research scientist at the Regenstrief Institute in Indianapolis, has received a prestigious Paul Beeson Emerging Leaders Career Development Award to support his work to advance the understanding of the role of oxidative stress in aging, focusing on the role of reactive oxygen species in cognitive impairment in patients with acute respiratory failure. The award provides up to five years of support and is a collaborative initiative of the National Institutes of Health’s National Institute on Aging, the American Federation for Aging Research and the John A. Hartford Foundation.

Khan’s research has focused on the nexus of acute respiratory failure, delirium in the intensive care unit and cognitive and physical function outcomes in critically ill older adults. His work has included measurement of delirium duration and severity, identification of delirium risk factors, exploration of delirium’s association with dementia through peripheral blood-based biomarkers, and testing of novel non-pharmacological interventions to mitigate delirium in the ICU.

In addition to his role as a research scientist, Khan is the co-director of the COVID-19 recovery program for older adults with the Indiana University Center for Aging Research, an assistant professor of medicine at Indiana University School of Medicine and director of the Indiana University Health Intensive Care Unit Survivor Center.

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