Selected publications:

1. Di Sole F and Babich V. New Insight into Adenosine Receptor Control of Salt and Fluid Homeostasis. MOJ Cell Science & Report 2016, 3(2): 00052
2. Abbattiscianni AC, Favia M, Mancini MT, Cardone RA, Guerra L, Monterisi S, Castellani S, Laselva O, Di Sole F, Conese M, Zaccolo M, Casavola V. Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization. J Cell Sci. 2016 Mar 15; 129(6): 1128-40
3. Babich V, Vadnagara K, Di Sole F. Dual effect of adenosine A₁ receptor activation on renal O₂ J Cell Physiol. 2015 Dec; 230(12): 3093-104
4. Babich V and Di Sole F. The Na⁺/H⁺ exchanger-3 activity requires ezrin binding to phosphoinositide and its phosphorylation. PLoS One. 2015 Jun 4; 10(6): e0129306.
5. Babich V, Vadnagara K, Di Sole F. The biophysical and molecular basis of intracellular pH sensing by the Na⁺/H⁺ exchanger-3. FASEB J. 2013 November; 27(11): 4646-4658
6. Antelmi E, Cardone RA, Greco MR, Rubino R, Di Sole F, Martino NA, Casavola V, Carcangiu M, Moro L, and Reshkin SJ. ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion. PLoS One. 2013 Sep 24; 8(9): e75113
7. Hu MC, Di Sole F, Zhang J, McLeroy P, Moe OW. Chronic regulation of the renal Na⁺/H⁺ exchanger NHE3 by dopamine: translational and post-translational mechanisms. Am J Physiol Renal Physiol. 2013 May; 304(9): F1169-80
8. Girardi AC, Di Sole F. Deciphering the mechanisms of the Na⁺/H⁺ exchanger-3 regulation in organ dysfunction. Review. Am J Physiol Cell Physiol. 2012; 302(11): C1569-87
9. Di Sole F, Vadnagara K, Moe OW, Babich V. Calcineurin Homologous Protein: A multi-functional Ca²⁺-binding protein family. Review. Am J Physiol Renal Physiol. 2012 Jul; 303(2): F165-79
10. Di Sole F, Girardi AC. Uncovering the pathway of sepsis-induced renal tubular dysfunction. Focus on “Basolateral LPS inhibits NHE3 and HCO absorption through TLR4/MyD88-dependent ERK activation in medullary thick ascending limb”. Am J Physiol Cell Physiol. 2011; 301(6): C1290-2
11. Di Sole F*, Hu MC*, Zhang J, Babich V, Bobulescu IA, McLeroy P, Rogers TE, Moe OW. Reduction of Na/H Exchanger-3 protein and transcript expression in acute ischemia-reperfusion is mediated by extractable tissue factor(s). Kidney Int. 2011 Oct; 80(8): 822-31. *These authors contributed equally to this work. Selected for the Journal Cover
12. Pao AC*, Bhargava A*, Di Sole F, Quigley R, Shao X, Wang J, Thomas S, Zhang J, Shi M, Funder JW, Moe OW, and Pearce D. Expression and role of serum and glucocorticoid regulated kinase 2 in the regulation of Na⁺/H⁺ exchanger 3 in mammalian kidney. Am J Physiol Renal Physiol. 2010; 299(6): F1496-1506. *These authors contributed equally to this work
13. Bobulescu IA*, Quiñones H*, Gisler SM, Di Sole F, Hu MC, Shi M, Zhang J, Fuster DG, Wright N, Mumby M, Moe OW. Acute regulation of renal Na⁺/H⁺ exchanger NHE3 by dopamine: role of protein phosphatase 2A. Am J Physiol Renal Physiol. 2010, 298(5): F1205-F1213. *These authors contributed equally to this work
14. Favia M, Guerra L, Fanelli T, Cardone RA, Monterisi S, Di Sole F, Castellani S, Chen M, Seidler U, Reshkin SJ, Conese M, and Casavola V. NHERF1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del CFTR in human airway CFBE41o-cells. Mol Biol Cell. 2010; 21(1): 73-86
15. Di Sole F, Babich V, Moe OW. The calcineurin homologous protein-1 increases Na⁺/H⁺-exchanger 3 trafficking via ezrin phosphorylation. J Am Soc Nephrol. 2009; 20(8): 1776-1786
16. Di Sole F. Adenosine and renal tubular function. Curr Opin Nephrol Hypertens. 2008; 17(4): 399-407
17. Di Sole F, Cerull R, Babich V, Casavola V, Helmle-Roth C, Burckhardt G. Short- and long-term A3 adenosine receptor activation inhibits the Na⁺/H⁺ exchanger NHE3 activity and expression in opossum kidney cells. J Cell Physiol. 2008; 216(1): 221-233.
18. Favia M, Fanelli T, Bagorda A, Di Sole F, Reshkin SJ, Suh PG, Guerra L, Casavola V. NHE3 inhibits PKA-dependent functional expression of CFTR by NHERF2 PDZ interactions. Biochem Biophys Res Commun. 2006; 347(2): 452-459.
19. Bobulescu IA, Di Sole F, Moe OW. Na⁺/H⁺ exchangers: physiology and link to hypertension and organ ischemia. Curr Opin Nephrol Hypertens. 2005; 14(5): 485-494
20. Di Sole F, Cerull R, Babich V, Quinones H, Gisler SM, Biber J, Murer H, Burckhardt G, Helmle-Kolb C, Moe OW. Acute regulation of Na/H exchanger NHE3 by adenosine A(1) receptors is mediated by calcineurin homologous protein. J Biol Chem. 2004; 279(4):2962-2974
21. Di Sole F, Cerull R, Petzke S, Casavola V, Burckhardt G, Helmle-Kolb C. Bimodal acute effects of A₁ adenosine receptor activation on Na⁺/H⁺ exchanger 3 in opossum kidney cells. J Am Soc Nephrol. 2003; 14(7): 1720-1730
22. Bagorda A, Guerra L, Di Sole F, Helmle-Kolb C, Favia M, Jacobson KA, Casavola V, Reshkin SJ Extracellular adenine nucleotides regulate Na⁺/H⁺ Exchanger NHE3 Activity in A₆-NHE3 transfectants by a cAMP/PKA-dependent mechanism. J Membr Biol. 2002; 188 (3):249-259
23. Di Sole F, Cerull R, Casavola V, Moe OW, Burckhardt G and Helmle-Kolb C. Molecular aspects of acute inhibition of Na⁺/H⁺ exchanger NHE3 by A₂-adenosine receptor agonists. J Physiol. 2002; 541 (Pt 2): 529-543
24. Bagorda A, Guerra L, Di Sole F, Hemle-Kolb C, Cardone RA, Fanelli T, Reshkin SJ, Gisler SM, Murer H, Casavola V. Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na⁺/H⁺ exchanger isoform 3 in a renal polarized epithelial cell model. J Biol Chem. 2002; 277 (24):21480-21488
25. Bruckhardt G, Di Sole F and Helmle-Kolb C. The Na⁺/H⁺ exchanger gene family. Review. Nephrol. 2002; 15 (5): S3-21